N-Acetyl Cysteine


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Liver Health

N-Acetyl Cysteine - Life Extension

Code: LE21 Size: 60 Strength: 600 mg Price: $17.99

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N-Acetyl Cysteine 600 Mg 60 Capsules N-acetyl-cysteine (NAC) is the acetylated form of L-cysteine that has been used to break up pulmonary and bronchial mucous.86-94 It is very efficiently absorbed and has been shown to protect cells directly.95-104 NAC is an antioxidant and a free radical-scavenging agent that increases intracellular glutathione at the cellular level. NAC can act as a precursor for glutathione synthesis as well as a stimulator of the cytosolic enzymes involved in glutathione regeneration. NAC has been shown to protect against oxidative stress-induced neuronal death in cultured granule neurons.105

NAC is an antioxidant that increases intracellular glutathione at the cellular level. NAC can act as a precursor for glutathione synthesis as well as a stimulator of the cytosolic enzymes involved in glutathione regeneration. NAC is the more efficiently absorbed and used form of the amino acid L-cysteine. L-cysteine plays a role in the sulfation cycle, acting as a sulfur donor16 in phase II detoxification and as a methyl donor in the conversion of homocysteine to methionine.17,18 N-acetyl cysteine also enhances immune function.19-22 NAC attenuates the progression of the abnormal retention of lipids within liver cells by decreasing development of oxidative stress and subsequent increases in TNF-alpha.23 In addition, N-acetyl cysteine is used to support bronchial health.24-27

Dosage and Use
Take one capsule one to three times daily with or without food, or as recommended by a healthcare practitioner.


1 tablet contains:

N-Acetyl Cysteine 600 mg



·    Other ingredients: gelatin, vegetable stearate, silica.

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Caution
Those who supplement with NAC should drink 6 to 8 glasses of water daily in order to prevent cysteine renal stones. Cysteine renal stones are rare but do occur.

Warnings

    
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17. J Clin Invest. 1989 Oct;84(4):1167-73.
18. Exp Physiol. 2008 Oct;93(10):1139-46. Epub 2008 Jun 20.
19. Neurochem Res. 2008 Oct 10. [Epub ahead of print]
20. Alzheimer Dis Assoc Disord.1995;9(3):128-31.
21. Neurochem Res.1995 Jan;20(1):1-9.
22. Mol Cell Biochem.2003 Dec;254(1-2):227-34
23. Int J Sport Nutr Exerc Metab.2008 Feb;18(1):19-36.
24. BMJ. 1991;32:1289-1290.
25. J Neurosci Res. 2001 Oct 15;66(2):266-71.
26. J Neurosci Res. 1991 Nov;30(3):555-9.
27. Eur J Pharmacol. 1992 Jul 21;218(1):117-21.
86. Acta Biochim Pol. 2004;51(2):405-13.
87. Eur J Hum Genet. 2003 Jan;11(1):23-9.
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90. Eur Respir J. 1997 Jul; 10(7): p1535-41.
91. J Immunol. 1994 Jun 15;152(12):5796-805.
92. Biochem Pharmacol. 1992 Mar 3;43(5):961-4.
93. Clin Pharmacokinet 1991 Feb; 20(2):123-34
94. Thorax. 1991 Jan;46(1):39-42.
95. Klin Wochenschr. 1991 Nov 15;69(18):857-62.
96. J Pharmacol Exp Ther. 1986 Feb;236(2):526-34.
97. Blood Purif. 2007;25(4):309-15. Epub 2007 Jul 20.
98. Kidney Int. 2007 Aug;72(3):359-63.
99. Kidney Int. 2007 Aug;72(3):231-2.
100. BMC Neurosci. 2007 Dec 6;8:106.
101. Biochem Pharmacol. 2008 Feb 1;75(3):773-80.
102. Environ Health Perspect. 2008 Jan;116(1):26-31.
103. J Cardiovasc Surg (Torino). 2008 Aug;49(4):527-31.
104. Int J Sport Nutr Exerc Metab. 2008 Aug;18(4):379-88.
105. Cerebellum. 2007 Jan 19:1-7.

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